Formyltetrahydrofolates

Tetrahydrofolates which are substituted by a formyl group at either the nitrogen atom in the 5 position or the nitrogen atom in the 10 position. N(5)-Formyltetrahydrofolate is leucovorin (citrovorum factor) while N(10)-formyltetrahydrofolate is an active coenzyme which functions as a carrier of the formyl group in a number of enzymatic reactions.

Year introduced: 1991 (1976)

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Tree Number(s): D03.633.100.733.631.400.800.350, D08.211.840.300

MeSH Unique ID: D005575

Entry Terms:

• N(10)-Formyltetrahydrofolate
• Formyltetrahydrofolic Acids

Previous Indexing:

• Citrovorum Factor (1966-1975)

Pharmacologic Action:

• Vitamin B Complex

All MeSH Categories
Chemicals and Drugs Category
Heterocyclic Compounds
Heterocyclic Compounds, Fused-Ring
Heterocyclic Compounds, 2-Ring
Pteridines
Pterins
Folic Acid
Tetrahydrofolates
Formyltetrahydrofolates
Leucovorin
Levoleucovorin

All MeSH Categories
Chemicals and Drugs Category
Enzymes and Coenzymes
Coenzymes
Tetrahydrofolates
Formyltetrahydrofolates
Leucovorin