Colforsin

Potent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant COLEUS FORSKOHLII. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities; also lowers intraocular pressure and promotes release of hormones from the pituitary gland.

Year introduced: 2014(1986)

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Tree Number(s): D02.455.849.291.300

MeSH Unique ID: D005576

Registry Number: 1F7A44V6OU

Entry Terms:

• Coleonol
• Forskolin
• N,N-Dimethyl-beta-alanine-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho(2,1-b)pyran-6-yl Ester HCl
• NKH 477
• NKH-477
• NKH477

Previous Indexing:

• Diterpenes (1974-1985)
• Terpenes (1966-1973)

Pharmacologic Action:

• Adjuvants, Immunologic
• Bronchodilator Agents
• Cardiotonic Agents
• Vasodilator Agents

All MeSH Categories
Chemicals and Drugs Category
Organic Chemicals
Hydrocarbons
Terpenes
Diterpenes
Colforsin