Guanylyl Imidodiphosphate
A non-hydrolyzable analog of GTP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It binds tightly to G-protein in the presence of Mg2+. The nucleotide is a potent stimulator of ADENYLYL CYCLASES.
Year introduced: 1991(1978)
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Subheadings:
Tree Number(s): D03.633.100.759.646.454.504.400, D13.695.667.454.504.400, D13.695.827.426.504.400
MeSH Unique ID: D006165
Registry Number: 34273-04-6
Entry Terms:
- Imidodiphosphate, Guanylyl
- Guanosine 5'-(Beta,Gamma-Imido)Triphosphate
- Guanyl-5'-Imidodiphosphate
- Guanyl 5' Imidodiphosphate
- Gpp(NH)p
- P(NH)PPG
- GMP-P(NH)P
- GMP-PNP
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