Immunoglobulin Idiotypes
Unique genetically-controlled determinants present on ANTIBODIES whose specificity is limited to a single group of proteins (e.g., another antibody molecule or an individual myeloma protein). The idiotype appears to represent the antigenicity of the antigen-binding site of the antibody and to be genetically codetermined with it. The idiotypic determinants have been precisely located to the IMMUNOGLOBULIN VARIABLE REGION of both immunoglobin polypeptide chains.
Year introduced: 1979
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Tree Number(s): D12.644.541.500.745, D12.776.124.486.485.680.745, D12.776.124.790.651.680.745, D12.776.377.715.548.680.745, D23.050.550.750, G02.111.570.060.425.580, G12.500.450
MeSH Unique ID: D007130
Entry Terms:
- Idiotype, Immunoglobulin
- Immunoglobulin Idiotype
- Ig Idiotypes
- Idiotype, Ig
- Idiotypes, Ig
- Ig Idiotype
- Idiotypes, Immunoglobulin
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