Interferon-gamma
The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.
Year introduced: 2009(1983)
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Tree Number(s): D12.644.276.374.440.893, D12.644.276.374.480.615.350, D12.776.467.374.440.893, D12.776.467.374.480.615.350, D23.529.374.440.893, D23.529.374.480.615.350
MeSH Unique ID: D007371
Registry Number: 82115-62-6
Entry Terms:
- Interferon Type II
- Interferon, gamma
- Interferon, Immune
- Immune Interferon
- Type II Interferon
- Interferon, Type II
- gamma-Interferon
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