Mitotane

A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.

Year introduced: 1973

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Tree Number(s): D02.455.526.439.681

MeSH Unique ID: D008939

Registry Number: 78E4J5IB5J

Entry Terms:

• ortho,para-DDD
• ortho,para DDD
• o,p-DDD
• Mytotan
• Lysodren
• Chlodithane
• Chloditan
• Khloditan

Previous Indexing:

• DDD/PD (1966-1972)

Pharmacologic Action:

• Antineoplastic Agents, Hormonal

All MeSH Categories
Chemicals and Drugs Category
Organic Chemicals
Hydrocarbons
Hydrocarbons, Halogenated
Hydrocarbons, Chlorinated
Mitotane