Mycophenolic Acid
Compound derived from Penicillium stoloniferum and related species. It blocks de novo biosynthesis of purine nucleotides by inhibition of the enzyme inosine monophosphate dehydrogenase (IMP DEHYDROGENASE). Mycophenolic acid exerts selective effects on the immune system in which it prevents the proliferation of T-CELLS, LYMPHOCYTES, and the formation of antibodies from B-CELLS. It may also inhibit recruitment of LEUKOCYTES to sites of INFLAMMATION.
Year introduced: 2017 (1999)
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Subheadings:
Tree Number(s): D02.241.081.193.678, D10.251.618
MeSH Unique ID: D009173
Registry Number: HU9DX48N0T
Entry Terms:
- Cellcept
- Mycophenolate Mofetil
- Mofetil, Mycophenolate
- Mycophenolic Acid Morpholinoethyl Ester
- RS 61443
- RS-61443
- RS61443
- Mycophenolate Mofetil Hydrochloride
- Mofetil Hydrochloride, Mycophenolate
- Myfortic
- Mycophenolate Sodium
- Sodium Mycophenolate
- Mycophenolate, Sodium
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Pharmacologic Action: