Neurosyphilis
Infections of the central nervous system caused by TREPONEMA PALLIDUM which present with a variety of clinical syndromes. The initial phase of infection usually causes a mild or asymptomatic meningeal reaction. The meningovascular form may present acutely as BRAIN INFARCTION. The infection may also remain subclinical for several years. Late syndromes include general paresis; TABES DORSALIS; meningeal syphilis; syphilitic OPTIC ATROPHY; and spinal syphilis. General paresis is characterized by progressive DEMENTIA; DYSARTHRIA; TREMOR; MYOCLONUS; SEIZURES; and Argyll-Robertson pupils. (Adams et al., Principles of Neurology, 6th ed, pp722-8)
Year introduced: 1963
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Subheadings:
Tree Number(s): C01.150.252.223.600, C01.150.252.400.794.840.500.750, C01.150.252.400.840.500.750, C01.207.180.600, C10.228.228.180.600
MeSH Unique ID: D009494
Entry Terms:
- Syphilis, Central Nervous System
- Central Nervous System Syphilis
- Syphilis, CNS
- General Paralysis
- General Paralysis of the Insane
- Paralysis, General
- General Paresis
- Paretic Neurosyphilis
- General Paresis of the Insane
- Juvenile Paresis
- Neurosyphilis, Asymptomatic
- Neurosyphilis, Gummatous
- Neurosyphilis, Juvenile
- Neurosyphilis, Secondary
- Secondary Neurosyphilis
- Neurosyphilis, Symptomatic