Pepsin A

Formed from pig pepsinogen by cleavage of one peptide bond. The enzyme is a single polypeptide chain and is inhibited by methyl 2-diaazoacetamidohexanoate. It cleaves peptides preferentially at the carbonyl linkages of phenylalanine or leucine and acts as the principal digestive enzyme of gastric juice.

Year introduced: 1991

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Tree Number(s): D08.811.277.656.074.500.700, D08.811.277.656.300.048.700

MeSH Unique ID: D010434

Registry Number: EC 3.4.23.1

Entry Terms:

• Pepsin
• Pepsin 1
• Pepsin 3

Pharmacologic Action:

• Gastrointestinal Agents

All MeSH Categories
Chemicals and Drugs Category
Enzymes and Coenzymes
Enzymes
Hydrolases
Peptide Hydrolases
Aspartic Acid Proteases
Aspartic Acid Endopeptidases
Pepsin A

All MeSH Categories
Chemicals and Drugs Category
Enzymes and Coenzymes
Enzymes
Hydrolases
Peptide Hydrolases
Endopeptidases
Aspartic Acid Endopeptidases
Pepsin A