Peptide Elongation Factor Tu
A protein found in bacteria and eukaryotic mitochondria which delivers aminoacyl-tRNA's to the A site of the ribosome. The aminoacyl-tRNA is first bound to a complex of elongation factor Tu containing a molecule of bound GTP. The resulting complex is then bound to the 70S initiation complex. Simultaneously the GTP is hydrolyzed and a Tu-GDP complex is released from the 70S ribosome. The Tu-GTP complex is regenerated from the Tu-GDP complex by the Ts elongation factor and GTP.
Year introduced: 1986
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Subheadings:
Tree Number(s): D08.811.277.040.330.300.100.700, D12.776.157.325.150.700, D12.776.476.338.100.700, D12.776.835.700.350.700
MeSH Unique ID: D010444
Registry Number: EC 3.6.1.-
Entry Terms:
- EF-Tu
- EF Tu
- Elongation Factor Tu
- Factor Tu, Elongation
- Protein Synthesis Elongation Factor Tu
- Eucaryotic Elongation Factor Tu
- eEF-Tu
- eEF Tu
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