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Tissue Plasminogen Activator

A proteolytic enzyme in the serine protease family found in many tissues which converts PLASMINOGEN to FIBRINOLYSIN. It has fibrin-binding activity and is immunologically different from UROKINASE-TYPE PLASMINOGEN ACTIVATOR. The primary sequence, composed of 527 amino acids, is identical in both the naturally occurring and synthetic proteases.

Year introduced: 1998(1986)

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Tree Number(s): D08.811.277.656.300.760.875, D08.811.277.656.959.350.875, D12.776.124.125.662.768, D23.119.970

MeSH Unique ID: D010959

Registry Number: EC 3.4.21.68

Entry Terms:

  • Plasminogen Activator, Tissue
  • Tissue Activator D-44
  • Tissue Activator D 44
  • Plasminogen Activator, Tissue-Type
  • Plasminogen Activator, Tissue Type
  • Tissue-Type Plasminogen Activator
  • Tissue Type Plasminogen Activator
  • TTPA
  • T-Plasminogen Activator
  • T Plasminogen Activator
  • Alteplase
  • Tisokinase
  • Actilyse
  • Lysatec rt-PA
  • Lysatec rtPA
  • Lysatec rt PA
  • Activase

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