Tissue Plasminogen Activator
A proteolytic enzyme in the serine protease family found in many tissues which converts PLASMINOGEN to FIBRINOLYSIN. It has fibrin-binding activity and is immunologically different from UROKINASE-TYPE PLASMINOGEN ACTIVATOR. The primary sequence, composed of 527 amino acids, is identical in both the naturally occurring and synthetic proteases.
Year introduced: 1998(1986)
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Subheadings:
Tree Number(s): D08.811.277.656.300.760.875, D08.811.277.656.959.350.875, D12.776.124.125.662.768, D23.119.970
MeSH Unique ID: D010959
Registry Number: EC 3.4.21.68
Entry Terms:
- Plasminogen Activator, Tissue
- Tissue Activator D-44
- Tissue Activator D 44
- Plasminogen Activator, Tissue-Type
- Plasminogen Activator, Tissue Type
- Tissue-Type Plasminogen Activator
- Tissue Type Plasminogen Activator
- TTPA
- T-Plasminogen Activator
- T Plasminogen Activator
- Alteplase
- Tisokinase
- Actilyse
- Lysatec rt-PA
- Lysatec rtPA
- Lysatec rt PA
- Activase
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