Polymyxin B
A mixture of polymyxins B1 and B2, obtained from BACILLUS POLYMYXA strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B is used for treatment of infections with gram-negative bacteria, but may be neurotoxic and nephrotoxic.
Year introduced: 1991(1978)
PubMed search builder options
Subheadings:
Tree Number(s): D04.345.566.780.750, D10.477.750.750, D12.644.050.600.750, D12.644.066.500.600.750, D12.644.641.780.750, D12.776.543.695.054.600.750
MeSH Unique ID: D011112
Registry Number: J2VZ07J96K
Entry Terms:
- Polymyxin B Sulfate
- Aerosporin
Pharmacologic Action: