Renin
A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19.
Year introduced: 1963
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Subheadings:
Tree Number(s): D08.811.277.656.074.500.780, D08.811.277.656.300.048.780, D08.811.277.656.837.750
MeSH Unique ID: D012083
Registry Number: EC 3.4.23.15
Entry Terms:
- Angiotensinogenase
- Angiotensin-Forming Enzyme
- Angiotensin Forming Enzyme
- Prorenin
- Big Renin
- Renin, Big
- Cryorenin
- Inactive Renin
- Renin, Inactive
- Preprorenin
- Pre-Prorenin
- Pre Prorenin