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Supranuclear Palsy, Progressive

A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al., Principles of Neurology, 6th ed, pp1076-7)

Year introduced: 1987

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Subheadings:

Tree Number(s): C10.228.140.079.882, C10.228.662.700, C10.292.562.750.500, C10.574.945.500, C10.597.622.447.690, C11.590.472.500, C23.888.592.636.447.690

MeSH Unique ID: D013494

Entry Terms:

  • Progressive Supranuclear Palsies
  • Supranuclear Palsies, Progressive
  • Palsy, Progressive Supranuclear
  • Progressive Supranuclear Palsy
  • Richardson's Syndrome
  • Richardson Syndrome
  • Steele-Richardson-Olszewski Disease
  • Steele Richardson Olszewski Disease
  • Steele-Richardson-Olszewski Syndrome
  • Steele Richardson Olszewski Syndrome
  • Ophthalmoplegia, Progressive Supranuclear
  • Supranuclear Ophthalmoplegia, Progressive
  • Progressive Supranuclear Ophthalmoplegia
  • Supranuclear Palsy, Progressive, 1
  • Progressive Supranuclear Palsy 1

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