Leukotrienes

A family of biologically active compounds derived from arachidonic acid by oxidative metabolism through the 5-lipoxygenase pathway. They participate in host defense reactions and pathophysiological conditions such as immediate hypersensitivity and inflammation. They have potent actions on many essential organs and systems, including the cardiovascular, pulmonary, and central nervous system as well as the gastrointestinal tract and the immune system.

Year introduced: 1989

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Tree Number(s): D10.251.355.255.100.450, D10.251.355.310.166.887, D23.469.050.175.450

MeSH Unique ID: D015289

Entry Terms:

• Leukotriene

Previous Indexing:

• Arachidonic Acids (1979-1988)
• Leukotrienes B (1983-1988)
• SRS-A (1979-1988)

See Also:

• Receptors, Leukotriene

All MeSH Categories
Chemicals and Drugs Category
Lipids
Fatty Acids
Fatty Acids, Unsaturated
Eicosanoids
Arachidonic Acids
Leukotrienes
Leukotriene A4
Leukotriene B4
SRS-A
Leukotriene C4
Leukotriene D4
Leukotriene E4

All MeSH Categories
Chemicals and Drugs Category
Lipids
Fatty Acids
Fatty Acids, Unsaturated
Fatty Acids, Essential
Arachidonic Acids
Leukotrienes
Leukotriene A4
Leukotriene B4
SRS-A
Leukotriene C4
Leukotriene D4
Leukotriene E4

All MeSH Categories
Chemicals and Drugs Category
Biological Factors
Inflammation Mediators
Autacoids
Eicosanoids
Leukotrienes
Leukotriene A4
Leukotriene B4
SRS-A
Leukotriene C4
Leukotriene D4
Leukotriene E4