Gene Rearrangement, B-Lymphocyte, Heavy Chain

Ordered rearrangement of B-lymphocyte variable gene regions of the IMMUNOGLOBULIN HEAVY CHAINS, thereby contributing to antibody diversity. It occurs during the first stage of differentiation of the IMMATURE B-LYMPHOCYTES.

Year introduced: 1989

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Do not include MeSH terms found below this term in the MeSH hierarchy.

Tree Number(s): G05.344.401.501, G12.500.274.501

MeSH Unique ID: D015326

Entry Terms:

• B Cell Heavy Chain Gene Rearrangement
• B-Cell Heavy Chain Gene Rearrangement
• B Lymphocyte Heavy Chain Gene Rearrangement
• B-Lymphocyte Heavy Chain Gene Rearrangement
• B-Lymphocyte Mu Chain Gene Rearrangement
• B Lymphocyte Mu Chain Gene Rearrangement
• B Cell Mu Chain Gene Rearrangement

Previous Indexing:

• B Lymphocytes/immunology (1977-1988)
• DNA/genetics (1977-1988)
• Genes, Immunoglobulin (1977-1988)
• Immunoglobulins, Heavy Chain/genetics (1977-1988)

All MeSH Categories
Phenomena and Processes Category
Genetic Phenomena
Gene Rearrangement
Gene Rearrangement, B-Lymphocyte
Gene Rearrangement, B-Lymphocyte, Heavy Chain
Immunoglobulin Class Switching

All MeSH Categories
Phenomena and Processes Category
Immune System Phenomena
Immunogenetic Phenomena
Gene Rearrangement, B-Lymphocyte
Gene Rearrangement, B-Lymphocyte, Heavy Chain
Immunoglobulin Class Switching