Retinoblastoma Protein
Product of the retinoblastoma tumor suppressor gene. It is a nuclear phosphoprotein hypothesized to normally act as an inhibitor of cell proliferation. Rb protein is absent in retinoblastoma cell lines. It also has been shown to form complexes with the adenovirus E1A protein, the SV40 T antigen, and the human papilloma virus E7 protein.
Year introduced: 1991
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Subheadings:
Tree Number(s): D12.776.260.704, D12.776.624.776.745, D12.776.660.807, D12.776.744.770
MeSH Unique ID: D016160
Entry Terms:
- Rb Gene Product
- Rb Protein
- Rb1 Gene Product
- p105-Rb Protein
- p105 Rb Protein
- Retinoblastoma Nuclear Phosphoprotein p105-Rb
- Retinoblastoma Nuclear Phosphoprotein p105 Rb
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