Granulocyte Colony-Stimulating Factor
A glycoprotein of MW 25 kDa containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines.
Year introduced: 1991
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Tree Number(s): D09.400.430.775.200, D12.644.276.374.410.240.350, D12.776.395.240.200, D12.776.467.374.410.240.350, D23.529.374.410.240.350
MeSH Unique ID: D016179
Registry Number: 143011-72-7
Entry Terms:
- Factor, Granulocyte Colony-Stimulating
- Granulocyte Colony Stimulating Factor
- Colony-Stimulating Factor, Granulocyte
- Colony Stimulating Factor, Granulocyte
- Myeloid Growth Factor
- Factor, Myeloid Growth
- Growth Factor, Myeloid
- G-CSF
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