Zinc Fingers
Motifs in DNA- and RNA-binding proteins whose amino acids are folded into a single structural unit around a zinc atom. In the classic zinc finger, one zinc atom is bound to two cysteines and two histidines. In between the cysteines and histidines are 12 residues which form a DNA binding fingertip. By variations in the composition of the sequences in the fingertip and the number and spacing of tandem repeats of the motif, zinc fingers can form a large number of different sequence specific binding sites.
Year introduced: 1991
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Subheadings:
Tree Number(s): G02.111.570.820.709.275.500.985
MeSH Unique ID: D016335
Entry Terms:
- Fingers, Zinc
- Finger, Zinc
- Zinc Finger
- Zinc Finger Motifs
- Motifs, Zinc Finger
- Motif, Zinc Finger
- Zinc Finger Motif
- Zinc Finger DNA-Binding Domains
- Zinc Finger DNA Binding Domains
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