Leucine Zippers

DNA-binding motifs formed from two alpha-helixes which intertwine for about eight turns into a coiled coil and then bifurcate to form Y shaped structures. Leucines occurring in heptad repeats end up on the same sides of the helixes and are adjacent to each other in the stem of the Y (the zipper region). The DNA-binding residues are located in the bifurcated region of the Y.

Year introduced: 1991

PubMed search builder options

Subheadings:

Restrict to MeSH Major Topic.

Do not include MeSH terms found below this term in the MeSH hierarchy.

Tree Number(s): G02.111.570.820.709.275.500.520

MeSH Unique ID: D016350

Entry Terms:

• Leucine Zipper
• Zipper, Leucine
• Zippers, Leucine

Previous Indexing:

• Amino Acid Sequence (1989-1990)
• DNA-Binding Proteins (1989-1990)
• Molecular Sequence Data (1989-1990)

All MeSH Categories
Phenomena and Processes Category
Chemical Phenomena
Biochemical Phenomena
Molecular Structure
Molecular Conformation
Protein Conformation
Protein Structural Elements
Amino Acid Motifs
Leucine Zippers