Mice, SCID

Mice homozygous for the mutant autosomal recessive gene scid which is located on the centromeric end of chromosome 16. These mice lack mature, functional lymphocytes and are thus highly susceptible to lethal opportunistic infections if not chronically treated with antibiotics. The lack of B- and T-cell immunity resembles severe combined immunodeficiency (SCID) syndrome in human infants. SCID mice are useful as animal models since they are receptive to implantation of a human immune system producing SCID-human (SCID-hu) hematochimeric mice.

Year introduced: 1992

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Tree Number(s): B01.050.150.900.649.313.992.635.505.500.550.780

MeSH Unique ID: D016513

Entry Terms:

• Immunodeficient Mice, Severe Combined
• Severe Combined Immunodeficient Mice
• Mouse, SCID
• SCID Mouse
• SCID Mice
• Mouse, SCID-hu
• Mouse, SCID hu
• SCID-hu Mouse
• SCID-hu Mice
• Mice, SCID-hu
• SCID hu Mice

Previous Indexing:

• Mice, Mutant Strains (1983-1991)

All MeSH Categories
Organisms Category
Eukaryota
Animals
Chordata
Vertebrates
Mammals
Eutheria
Rodentia
Muridae
Murinae
Mice
Mice, Mutant Strains
Mice, SCID