CD3 Complex
Complex of at least five membrane-bound polypeptides in mature T-lymphocytes that are non-covalently associated with one another and with the T-cell receptor (RECEPTORS, ANTIGEN, T-CELL). The CD3 complex includes the gamma, delta, epsilon, zeta, and eta chains (subunits). When antigen binds to the T-cell receptor, the CD3 complex transduces the activating signals to the cytoplasm of the T-cell. The CD3 gamma and delta chains (subunits) are separate from and not related to the gamma/delta chains of the T-cell receptor (RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA).
Year introduced: 2018 (1993)
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Subheadings:
Tree Number(s): D23.050.301.264.894.095, D23.101.100.894.095
MeSH Unique ID: D017252
Entry Terms:
- T3 Antigen
- Antigen, T3
- T3 Antigens
- Antigens, T3
- CD3 Antigen
- Antigen, CD3
- CD3 Antigens
- Antigens, CD3
- T3 Complex
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