CD3 Complex

Complex of at least five membrane-bound polypeptides in mature T-lymphocytes that are non-covalently associated with one another and with the T-cell receptor (RECEPTORS, ANTIGEN, T-CELL). The CD3 complex includes the gamma, delta, epsilon, zeta, and eta chains (subunits). When antigen binds to the T-cell receptor, the CD3 complex transduces the activating signals to the cytoplasm of the T-cell. The CD3 gamma and delta chains (subunits) are separate from and not related to the gamma/delta chains of the T-cell receptor (RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA).

Year introduced: 2018 (1993)

PubMed search builder options

Subheadings:

Restrict to MeSH Major Topic.

Do not include MeSH terms found below this term in the MeSH hierarchy.

Tree Number(s): D23.050.301.264.894.095, D23.101.100.894.095

MeSH Unique ID: D017252

Entry Terms:

• T3 Antigen
• Antigen, T3
• T3 Antigens
• Antigens, T3
• CD3 Antigen
• Antigen, CD3
• CD3 Antigens
• Antigens, CD3
• T3 Complex

Previous Indexing:

• Antigens (1983-1984)
• Antigens, Differentiation, T-Lymphocyte (1988-1992)
• Antigens, Surface (1983-1987)
• Receptors, Antigen, T-Cell (1990-1992)

See Also:

• Receptors, Antigen, T-Cell

All MeSH Categories
Chemicals and Drugs Category
Biological Factors
Antigens
Antigens, Surface
Antigens, Differentiation
Antigens, Differentiation, T-Lymphocyte
CD3 Complex
Receptor-CD3 Complex, Antigen, T-Cell

All MeSH Categories
Chemicals and Drugs Category
Biological Factors
Biomarkers
Antigens, Differentiation
Antigens, Differentiation, T-Lymphocyte
CD3 Complex
Receptor-CD3 Complex, Antigen, T-Cell