Receptors, Somatomedin

Cell surface receptors that bind somatomedins and trigger intracellular changes which influence the behavior of cells. Studies have disclosed two types of receptors for this family of peptide hormones. The type I receptor is homologous to the insulin receptor and has tyrosine kinase activity. The type II receptor is identical to the mannose-6-phosphate receptor which is important in trafficking of lysosomal enzymes.

Year introduced: 1993

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Tree Number(s): D12.776.543.750.750.400.780

MeSH Unique ID: D017451

Entry Terms:

• Insulin-Like Growth Factor Receptor
• Insulin Like Growth Factor Receptor
• Insulin-Like Growth Factor Receptors
• Insulin Like Growth Factor Receptors
• Receptors, Insulin-Like Growth Factors
• Receptors, Insulin Like Growth Factors
• Somatomedin Receptor
• Receptor, Somatomedin
• Somatomedin Receptors

Previous Indexing:

• Receptors, Endogenous Substances (1980-1992)
• Receptors, Insulin (1980-1989)

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Membrane Proteins
Receptors, Cell Surface
Receptors, Peptide
Receptors, Growth Factor
Receptors, Somatomedin
Receptor, IGF Type 1
Receptor, IGF Type 2