Receptors, Platelet-Derived Growth Factor
Specific receptors on cell membranes that react with PLATELET-DERIVED GROWTH FACTOR, its analogs, or antagonists. The alpha PDGF receptor (RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA) and the beta PDGF receptor (RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA) are the two principle types of PDGF receptors. Activation of the protein-tyrosine kinase activity of the receptors occurs by ligand-induced dimerization or heterodimerization of PDGF receptor types.
Year introduced: 1993
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Tree Number(s): D08.811.913.696.620.682.725.400.900, D12.776.476.568.400.900, D12.776.543.750.630.625, D12.776.543.750.750.400.630
MeSH Unique ID: D017479
Registry Number: EC 2.7.10.1
Entry Terms:
- Receptors, Platelet Derived Growth Factor
- Platelet-Derived Growth Factor Receptor
- Platelet Derived Growth Factor Receptor
- Platelet-Derived Growth Factor Receptors
- Platelet Derived Growth Factor Receptors
- PDGF Receptor
- Receptor, PDGF
- PDGF Receptors
- Receptors, PDGF
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