Receptors, sigma
A class of cell surface receptors recognized by its pharmacological profile. Sigma receptors were originally considered to be opioid receptors because they bind certain synthetic opioids. However they also interact with a variety of other psychoactive drugs, and their endogenous ligand is not known (although they can react to certain endogenous steroids). Sigma receptors are found in the immune, endocrine, and nervous systems, and in some peripheral tissues.
Year introduced: 1993
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Subheadings:
Tree Number(s): D12.776.543.750.695.620.775, D12.776.543.750.720.600.610.775, D12.776.543.750.750.555.610.775
MeSH Unique ID: D017480
Entry Terms:
- Receptors, sigma Opioid
- sigma Receptor
- Receptor, sigma
- sigma Receptors
- Opioid Receptors, sigma
- sigma Opioid Receptors
- Receptors, Opioid, sigma
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