Genes, erbB-2
The erbB-2 gene is a proto-oncogene that codes for the erbB-2 receptor (RECEPTOR, ERBB-2), a protein with structural features similar to the epidermal growth factor receptor. Its name originates from the viral oncogene homolog (v-erbB) which is a truncated form of the chicken erbB gene found in the avian erythroblastosis virus. Overexpression and amplification of the gene is associated with a significant number of adenocarcinomas. The human c-erbB-2 gene is located at 17q21.2.
Year introduced: 1995
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Subheadings:
Tree Number(s): G05.360.340.024.340.375.500.791.295.305
MeSH Unique ID: D018734
Entry Terms:
- c-erbB-2 Genes
- c-erbB-2 Gene
- c erbB 2 Genes
- c-erbB-2 Proto-Oncogenes
- c-erbB-2 Proto-Oncogene
- c erbB 2 Proto Oncogenes
- Genes, HER-2
- HER-2 Gene
- HER-2 Genes
- Genes, neu
- neu Gene
- neu Genes
- Genes, HER2
- Gene, HER2
- HER2 Gene
- HER2 Genes
- erbB-2 Genes
- erbB-2 Gene
- erbB 2 Genes
- Genes, erbb2
- erbb2 Gene
- erbb2 Genes
- Gene, erbb2
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