Genes, erbB-1
The proto-oncogene c-erbB-1 codes for the epidermal growth factor receptor. Its name originates from the viral homolog v-erbB which was isolated from an avian erythroblastosis virus (AEV) where it was contained as a fragment of the chicken c-ErbB-1 gene lacking the amino-terminal ligand-binding domain. Overexpression of erbB-1 genes occurs in a wide range of tumors, commonly squamous carcinomas of various sites and less commonly adenocarcinomas. The human c-erbB-1 gene is located in the chromosomal region 7p14 and 7p12.
Year introduced: 1995
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Subheadings:
Tree Number(s): G05.360.340.024.340.375.500.791.295.300
MeSH Unique ID: D018773
Entry Terms:
- erbB-1 Genes
- erbB-1 Gene
- erbB 1 Genes
- Genes, erbB1
- erbB1 Gene
- erbB1 Genes
- Gene, erbB1
- c-erbB-1 Genes
- c-erbB-1 Gene
- c erbB 1 Genes
- Epidermal Growth Factor Receptor Genes
- EGFR Genes
- c-erbB-1 Proto-Oncogenes
- c-erbB-1 Proto-Oncogene
- c erbB 1 Proto Oncogenes
- Genes, EGFR
- EGFR Gene
- v-erbB Genes
- v-erbB Gene
- v erbB Genes
- v-erbB Oncogenes
- v-erbB Oncogene
- v erbB Oncogenes
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