DNA Footprinting
A method for determining the sequence specificity of DNA-binding proteins. DNA footprinting utilizes a DNA damaging agent (either a chemical reagent or a nuclease) which cleaves DNA at every base pair. DNA cleavage is inhibited where the ligand binds to DNA. (from Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
Year introduced: 1996
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Subheadings:
Tree Number(s): E05.393.300
MeSH Unique ID: D018983
Entry Terms:
- DNA Footprintings
- Footprinting, DNA
- Footprintings, DNA
- Footprints, DNA
- DNA Footprint
- DNA Footprints
- Footprint, DNA