Lymphocyte Specific Protein Tyrosine Kinase p56(lck)
This enzyme is a lymphoid-specific src family tyrosine kinase that is critical for T-cell development and activation. Lck is associated with the cytoplasmic domains of CD4, CD8 and the beta-chain of the IL-2 receptor, and is thought to be involved in the earliest steps of TCR-mediated T-cell activation.
Year introduced: 1998
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Subheadings:
Tree Number(s): D08.811.913.696.620.682.725.800.315, D12.776.476.568.800.315, D12.776.624.664.700.128
MeSH Unique ID: D019860
Registry Number: EC 2.7.10.2
Entry Terms:
- Proto-Oncogene Protein c-lck
- c-lck, Proto-Oncogene Protein
- Protein c-lck, Proto-Oncogene
- Proto Oncogene Protein c lck
- p56 lck
- Protein Tyrosine Kinase p56(lck)
- lck Kinase
- Kinase, lck
- Proto-Oncogene Protein lck
- lck, Proto-Oncogene Protein
- Protein lck, Proto-Oncogene
- Proto Oncogene Protein lck
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