Paraneoplastic Cerebellar Degeneration
Cerebellar degeneration associated with a remote neoplasm. Clinical manifestations include progressive limb and GAIT ATAXIA; DYSARTHRIA; and NYSTAGMUS, PATHOLOGIC. The histologic type of the associated neoplasm is usually carcinoma or lymphoma. Pathologically the cerebellar cortex and subcortical nuclei demonstrate diffuse degenerative changes. Anti-Purkinje cell antibodies (anti-Yo) are found in the serum of approximately 50% of affected individuals. (Adams et al., Principles of Neurology, 6th ed, p686)
Year introduced: 2000
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Subheadings:
Tree Number(s): C04.588.614.550.650, C04.730.856.650, C10.228.140.252.620, C10.574.781.700
MeSH Unique ID: D020362
Entry Terms:
- Degeneration, Paraneoplastic Cerebellar
- Cerebellar Degeneration, Paraneoplastic
- Cerebellar Syndrome, Paraneoplastic
- Cerebellar Syndromes, Paraneoplastic
- Paraneoplastic Cerebellar Syndromes
- Paraneoplastic Cerebellar Syndrome
- Paraneoplastic Cerebellar Degeneration, Anti-Yo-Associated
- Paraneoplastic Cerebellar Degeneration, Anti Yo Associated
- Anti-Yo-Associated Paraneoplastic Cerebellar Degeneration
- Anti Yo Associated Paraneoplastic Cerebellar Degeneration
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