I-kappa B Proteins

A family of inhibitory proteins which bind to the REL PROTO-ONCOGENE PROTEINS and modulate their activity. In the CYTOPLASM, I-kappa B proteins bind to the transcription factor NF-KAPPA B. Cell stimulation causes its dissociation and translocation of active NF-kappa B to the nucleus.

Year introduced: 2006(2000)

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Tree Number(s): D12.644.360.365, D12.776.260.420, D12.776.476.381, D12.776.930.326

MeSH Unique ID: D020672

Entry Terms:

• I kappa B Proteins
• I-kappa B
• I kappa B
• IkB DNA-Binding Proteins
• IkB DNA Binding Proteins

Previous Indexing:

• DNA-Binding Proteins (1998-1999)
• Proto-Oncogene Proteins (1993-1998)

See Also:

• NF-kappa B
• Proto-Oncogene Proteins c-rel
• I-kappa B Kinase

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Peptides
Intracellular Signaling Peptides and Proteins
I-kappa B Proteins
NF-KappaB Inhibitor alpha

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
DNA-Binding Proteins
I-kappa B Proteins
NF-KappaB Inhibitor alpha

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Intracellular Signaling Peptides and Proteins
I-kappa B Proteins
NF-KappaB Inhibitor alpha

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Transcription Factors
I-kappa B Proteins
NF-KappaB Inhibitor alpha