Vigabatrin

An analogue of GAMMA-AMINOBUTYRIC ACID. It is an irreversible inhibitor of 4-AMINOBUTYRATE TRANSAMINASE, the enzyme responsible for the catabolism of GAMMA-AMINOBUTYRIC ACID and is used as an anticonvulsant. (From Martindale The Extra Pharmacopoeia, 31st ed)

Year introduced: 2000

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Tree Number(s): D02.241.081.114.500.350.900, D12.125.190.350.900

MeSH Unique ID: D020888

Registry Number: GR120KRT6K

Entry Terms:

• gamma-Vinyl-GABA
• gamma Vinyl GABA
• gamma-Vinyl-gamma-Aminobutyric Acid
• gamma Vinyl gamma Aminobutyric Acid
• Sabril
• Sabrilex

Previous Indexing:

• Aminocaproic Acids (1981-1994)
• GABA/analogs and derivatives (1979-1980)
• GABA/analogs and derivatives (1994-1999)

Pharmacologic Action:

• Anticonvulsants
• Enzyme Inhibitors
• GABA Agents

All MeSH Categories
Chemicals and Drugs Category
Organic Chemicals
Carboxylic Acids
Acids, Acyclic
Butyrates
Aminobutyrates
gamma-Aminobutyric Acid
Vigabatrin

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Amino Acids
Aminobutyrates
gamma-Aminobutyric Acid
Vigabatrin