Conotoxins
Peptide neurotoxins from the marine fish-hunting snails of the genus CONUS. They contain 13 to 29 amino acids which are strongly basic and are highly cross-linked by disulfide bonds. There are three types of conotoxins, omega-, alpha-, and mu-. OMEGA-CONOTOXINS inhibit voltage-activated entry of calcium into the presynaptic membrane and therefore the release of ACETYLCHOLINE. Alpha-conotoxins inhibit the postsynaptic acetylcholine receptor. Mu-conotoxins prevent the generation of muscle action potentials. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)
Year introduced: 2000
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Subheadings:
Tree Number(s): D20.888.590.162, D23.946.580.590.162, D23.946.833.590.162
MeSH Unique ID: D020916
Entry Terms:
- Conotoxin
- alpha-Conotoxins
- alpha Conotoxins
- alpha-Conotoxin
- alpha Conotoxin
- mu-Conotoxins
- mu Conotoxins
- mu-Conotoxin
- mu Conotoxin
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