Mitogen-Activated Protein Kinase Kinases
A dual-specific protein kinase family whose members are components in protein kinase cascades activated by diverse stimuli. These MAPK kinases phosphorylate MITOGEN-ACTIVATED PROTEIN KINASES and are themselves phosphorylated by MAP KINASE KINASE KINASES. JNK kinases (also known as SAPK kinases) are a subfamily.
Year introduced: 2000
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Tree Number(s): D08.811.913.696.620.682.700.565, D08.811.913.696.620.682.725.200, D12.776.476.563.565, D12.776.476.568.200
MeSH Unique ID: D020929
Registry Number: EC 2.7.12.2
Entry Terms:
- Mitogen Activated Protein Kinase Kinases
- MAPK Kinase
- Kinase, MAPK
- Map Kinase Kinase
- Kinase Kinase, Map
- Kinase, Map Kinase
- MAPKK
- MAP Kinase Kinases
- Kinase Kinases, MAP
- Kinases, MAP Kinase
- MAPK Kinases
- Kinases, MAPK
- Mitogen-Activated Protein Kinase Kinase
- Mitogen Activated Protein Kinase Kinase
- MAPKKs
- MAPK-ERK Kinases
- Kinases, MAPK-ERK
- MAPK ERK Kinases
- MAPK-ERK Kinase
- Kinase, MAPK-ERK
- MAPK ERK Kinase
- MEK
- MAP-ERK Kinase
- Kinase, MAP-ERK
- MAP ERK Kinase
- MEKs
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