Striatonigral Degeneration

A sporadic neurodegenerative disease with onset in middle-age characterized clinically by Parkinsonian features (e.g., MUSCLE RIGIDITY; HYPOKINESIA; stooped posture) and HYPOTENSION. This condition is considered a clinical variant of MULTIPLE SYSTEM ATROPHY. Pathologic features include a prominent loss of neurons in the zona compacta of the SUBSTANTIA NIGRA and PUTAMEN. (From Adams et al., Principles of Neurology, 6th ed, p1075-6)

Year introduced: 2000

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Do not include MeSH terms found below this term in the MeSH hierarchy.

Tree Number(s): C10.177.575.550.875, C10.228.140.079.612.800, C10.228.662.550.800

MeSH Unique ID: D020955

Entry Terms:

• Degeneration, Striatonigral
• Striatonigral Degenerations
• Striatonigral Atrophy
• Atrophies, Striatonigral
• Atrophy, Striatonigral
• Striatonigral Atrophies

Previous Indexing:

• Multiple System Atrophy (1998-1999)
• Parkinson Disease (1970-1993)
• Substantia Nigra (1970-1999)

See Also:

• Parkinsonian Disorders

All MeSH Categories
Diseases Category
Nervous System Diseases
Autonomic Nervous System Diseases
Primary Dysautonomias
Multiple System Atrophy
Striatonigral Degeneration

All MeSH Categories
Diseases Category
Nervous System Diseases
Central Nervous System Diseases
Brain Diseases
Basal Ganglia Diseases
Multiple System Atrophy
Striatonigral Degeneration

All MeSH Categories
Diseases Category
Nervous System Diseases
Central Nervous System Diseases
Movement Disorders
Multiple System Atrophy
Striatonigral Degeneration