HMG-Box Domains

DNA-binding domains present in proteins of the HMG-box superfamily including the archetypal HMGB PROTEINS, a number of sequence specific TRANSCRIPTION FACTORS, and other DNA-BINDING PROTEINS. The domains consist of 70-80 amino acids that form an L-shaped fold from three alpha-helical segments. The domain has the capacity to recognize and/or induce specific DNA structures and effect the accessibility of the DNA to other proteins involved in transcription, recombination, or DNA repair. (Note that not all HIGH MOBILITY GROUP PROTEINS contain this domain.)

Year introduced: 2002

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Tree Number(s): G02.111.570.820.709.275.750.235

MeSH Unique ID: D024742

Entry Terms:

• Domain, HMG-Box
• Domains, HMG-Box
• HMG Box Domains
• HMG-1-Box Domain
• Domain, HMG-1-Box
• Domains, HMG-1-Box
• HMG 1 Box Domain
• HMG-1-Box Domains
• High Mobility Group-Box Domains
• High Mobility Group Box Domains
• HMG-Box Domain
• HMG Box Domain

Previous Indexing:

• High Mobility Group Proteins (1991-2001)

All MeSH Categories
Phenomena and Processes Category
Chemical Phenomena
Biochemical Phenomena
Molecular Structure
Molecular Conformation
Protein Conformation
Protein Structural Elements
Protein Domains
HMG-Box Domains