Hydroxymethylglutaryl-CoA Reductases, NAD-Dependent

Specific hydroxymethylglutaryl CoA reductases that utilize the cofactor NAD. This class of enzymes performs a catabolic role in microorganisms such as Pseudomonas mevalonii where it oxidatively acetylates MEVALONIC ACID to form 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A and NADH.

Year introduced: 2002

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Tree Number(s): D08.811.682.047.820.150.415.250

MeSH Unique ID: D025781

Registry Number: EC 1.1.1.88

Entry Terms:

• NAD-Dependent Hydroxymethylglutaryl-CoA Reductases
• HMG CoA Reductase, NAD-Dependent
• HMG CoA Reductase, NAD Dependent
• HMG CoA Reductases, NAD-Dependent
• HMG CoA Reductases, NAD Dependent
• Hydroxymethylglutaryl CoA Reductase, NAD-Dependent
• Hydroxymethylglutaryl CoA Reductase, NAD Dependent
• 3-Hydroxy-3-methylglutaryl CoA-Reductase, NAD-Dependent
• CoA-Reductase, NAD-Dependent 3-Hydroxy-3-methylglutaryl
• NAD-Dependent 3-Hydroxy-3-methylglutaryl CoA-Reductase

Previous Indexing:

• Hydroxymethylglutaryl CoA Reductases (1989-2001)

All MeSH Categories
Chemicals and Drugs Category
Enzymes and Coenzymes
Enzymes
Oxidoreductases
Alcohol Oxidoreductases
NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases
3-Hydroxyacyl CoA Dehydrogenases
Hydroxymethylglutaryl CoA Reductases
Hydroxymethylglutaryl-CoA Reductases, NAD-Dependent