beta Karyopherins
Nucleocytoplasmic transport molecules that bind to ALPHA KARYOPHERINS in the CYTOSOL and are involved in transport of molecules through the NUCLEAR PORE COMPLEX. Once inside the CELL NUCLEUS beta karyopherins interact with RAN GTP-BINDING PROTEIN and dissociate from alpha karyopherins. Beta karyopherins bound to RAN GTP-BINDING PROTEIN are then re-transported to the cytoplasm where hydrolysis of the GTP of RAN GTP-BINDING PROTEIN causes release of karyopherin beta.
Year introduced: 2002
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Subheadings:
Tree Number(s): D12.776.157.530.750.500.249, D12.776.543.585.750.500.249, D12.776.660.502.500
MeSH Unique ID: D028961
Entry Terms:
- Karyopherins, beta
- Kap95 protein
- p92 nuclear protein
- nuclear protein, p92
- Karyopherin beta
- Karyopherin-beta
- Karyopherin-beta Subunit
- Karyopherin beta Subunit
- Importin-beta
- Importin beta
- beta Importins
- Importins, beta
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