Epothilones

A group of 16-member MACROLIDES which stabilize MICROTUBULES in a manner similar to PACLITAXEL. They were originally found in the myxobacterium Sorangium cellulosum, now renamed to Polyangium (MYXOCOCCALES).

Year introduced: 2003

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Tree Number(s): D02.540.576.500.984

MeSH Unique ID: D034261

Entry Terms:

• Epothilon
• Epothilone

Previous Indexing:

• Epoxy Compounds (1995-2002)
• Macrolides (1998-2002)

Pharmacologic Action:

• Tubulin Modulators

All MeSH Categories
Chemicals and Drugs Category
Organic Chemicals
Lactones
Polyketides
Macrolides
Epothilones