Heterogeneous-Nuclear Ribonucleoprotein K
A heterogeneous-nuclear ribonucleoprotein found in the CELL NUCLEUS and the CYTOPLASM. Heterogeneous-nuclear ribonucleoprotein K has been implicated in the regulation of gene expression at nearly all levels: GENETIC TRANSCRIPTION; mRNA processing (RNA PROCESSING, POST-TRANSCRIPTIONAL), mRNA transport, mRNA stability, and translation (TRANSLATION, GENETIC). The hnRNP protein has a strong affinity for polypyrimidine-rich RNA and for single-stranded polypyrimidine-rich DNA. Multiple hnRNP K protein isoforms exist due to alternative splicing and display different nucleic-acid-binding properties.
Year introduced: 2003
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Subheadings:
Tree Number(s): D12.776.157.725.500.313.500, D12.776.157.725.813.750.500, D12.776.260.268, D12.776.664.962.500.313.500, D12.776.664.962.813.750.500
MeSH Unique ID: D034641
Entry Terms:
- Heterogeneous Nuclear Ribonucleoprotein K
- Ribonucleoprotein K, Heterogeneous-Nuclear
- hnRNP K
- hnRNP K Protein
- dC-Stretch-Binding Protein
- dC Stretch Binding Protein
- Heterogeneous Nuclear Ribonucleoprotein Particle K Protein
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