Thyroid Hormone Receptors beta
High affinity receptors for THYROID HORMONES, especially TRIIODOTHYRONINE. These receptors are usually found in the nucleus where they regulate DNA transcription. They are encoded by the THRB gene (also known as NR1A2, THRB1, or ERBA2 gene) as several isoforms produced by alternative splicing. Mutations in the THRB gene cause THYROID HORMONE RESISTANCE SYNDROME.
Year introduced: 2003
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Subheadings:
Tree Number(s): D12.776.624.664.700.830.750, D12.776.826.850.750
MeSH Unique ID: D037042
Entry Terms:
- c-erbA beta
- c erbA beta
- TR beta
- THRB Gene Products
- Gene Products, THRB
- ERBA2 Gene Products
- Gene Products, ERBA2
- NR1A2 Gene Products
- Gene Products, NR1A2
- Receptors beta, Thyroid Hormone
- Thyroid Hormone Receptor beta
- Thyroid Hormone Receptor beta-1
- Thyroid Hormone Receptor beta 1
- Thyroid Hormone Receptor beta-2
- Thyroid Hormone Receptor beta 2