Pulmonary Surfactant-Associated Protein A

An abundant pulmonary surfactant-associated protein that binds to a variety of lung pathogens, resulting in their opsinization. It also stimulates MACROPHAGES to undergo PHAGOCYTOSIS of microorganisms. Surfactant protein A contains a N-terminal collagen-like domain and a C-terminal lectin domain that are characteristic of members of the collectin family of proteins.

Year introduced: 2003

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Tree Number(s): D12.776.503.280.249.600, D12.776.823.100

MeSH Unique ID: D037662

Entry Terms:

• Pulmonary Surfactant Associated Protein A
• SP-A Protein
• SP A Protein
• Surfactant Protein A

Previous Indexing:

• Proteolipids (1991-2002)
• Pulmonary Surfactants (1991-2002)

Pharmacologic Action:

• Pulmonary Surfactants

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Lectins
Lectins, C-Type
Collectins
Pulmonary Surfactant-Associated Protein A

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Pulmonary Surfactant-Associated Proteins
Pulmonary Surfactant-Associated Protein A