Follistatin

A broadly distributed protein that binds directly to ACTIVINS. It functions as an activin antagonist, inhibits FOLLICLE STIMULATING HORMONE secretion, regulates CELL DIFFERENTIATION, and plays an important role in embryogenesis. Follistatin is a single glycosylated polypeptide chain of approximately 37-kDa and is not a member of the inhibin family (INHIBINS). Follistatin also binds and neutralizes many members of the TRANSFORMING GROWTH FACTOR BETA family.

Year introduced: 2003

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Tree Number(s): D12.776.157.247

MeSH Unique ID: D038681

Entry Terms:

• Activin-Binding Protein
• Activin Binding Protein

Previous Indexing:

• Activins (2002)
• Glycoproteins (1987-2001)
• Inhibins (1987-2001)

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Carrier Proteins
Follistatin