Semaphorin-3A
The prototypical and most well-studied member of the semaphorin family. Semaphorin-3A is an axon-repulsive guidance cue for migrating neurons in the developing nervous system. It has so far been found only in vertebrates, and binds to NEUROPILIN-1/plexin complex receptors on growth cones. Like other class 3 semaphorins, it is a secreted protein.
Year introduced: 2003
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Subheadings:
Tree Number(s): D12.644.276.923.374, D12.776.467.923.374, D23.529.923.374
MeSH Unique ID: D040121
Entry Terms:
- Sem D
- Semaphorin D
- Collapsin
- Sema3A
- Semaphorin 3A
- Collapsing Factor
- Collapsin-1
- Collapsin 1
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