Calgranulin A
A 10.8-kDa member of the S-100 family of calcium-binding proteins that can form homo- or heterocomplexes with CALGRANULIN B and a variety of other proteins. The calgranulin A/B heterodimer is known as LEUKOCYTE L1 ANTIGEN COMPLEX. Calgranulin A is found in many cell types including GRANULOCYTES; KERATINOCYTES; and myelomonocytes, and has been shown to act as a chemotactic substance for NEUTROPHILS. Because it is present in acute inflammation but absent in chronic inflammation, it is a useful biological marker for a number of pathological conditions.
Year introduced: 2003
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Subheadings:
Tree Number(s): D12.776.157.125.750.500.100, D12.776.631.658.750.500, D23.050.301.562.100
MeSH Unique ID: D040501
Entry Terms:
- Cystic Fibrosis Antigen
- Antigen, Cystic Fibrosis
- 60B8-B Antigen
- 60B8 B Antigen
- Antigen, 60B8-B
- CABP-P8
- MRP8 Protein
- Macrophage-Related Protein-8
- Macrophage Related Protein 8
- Myeloid Calcium-Binding Protein P8
- Myeloid Calcium Binding Protein P8
- MRP-8 Protein
- MRP 8 Protein
- S100 A8 Protein
- A8 Protein, S100
- S100A8 Protein
- Leukocyte L1 Protein Light Chain
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