Angiopoietin-2

An angiopoietin that is closely related to ANGIOPOIETIN-1. It binds to the TIE-2 RECEPTOR without receptor stimulation and antagonizes the effect of ANGIOPOIETIN-1. However its antagonistic effect may be limited to cell receptors that occur within the vasculature. Angiopoietin-2 may therefore play a role in down-regulation of BLOOD VESSEL branching and sprouting.

Year introduced: 2004

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Tree Number(s): D12.644.276.100.100.200, D12.776.467.100.100.200, D23.529.100.100.200

MeSH Unique ID: D042702

Entry Terms:

• Angiopoietin 2

Previous Indexing:

• Angiogenesis Factor (2003)
• Proteins (1999-2002)

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Peptides
Intercellular Signaling Peptides and Proteins
Angiogenic Proteins
Angiopoietins
Angiopoietin-2

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Intercellular Signaling Peptides and Proteins
Angiogenic Proteins
Angiopoietins
Angiopoietin-2

All MeSH Categories
Chemicals and Drugs Category
Biological Factors
Intercellular Signaling Peptides and Proteins
Angiogenic Proteins
Angiopoietins
Angiopoietin-2