Positive Transcriptional Elongation Factor B

A transcriptional elongation factor complex that is comprised of a heterodimer of CYCLIN-DEPENDENT KINASE 9 and one of several CYCLINS including TYPE T CYCLINS and cyclin K. It functions by phosphorylating the carboxy-terminal domain of RNA POLYMERASE II.

Year introduced: 2004

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Tree Number(s): D08.811.913.696.620.682.700.626, D12.776.476.563.626, D12.776.930.955.500

MeSH Unique ID: D042925

Registry Number: EC 2.7.11.-

Entry Terms:

• P-TEFb
• tat-Associated Kinase
• tat Associated Kinase
• Positive Transcription Elongation Factor B

Previous Indexing:

• Protein-Serine-Threonine Kinases (1996-2003)

All MeSH Categories
Chemicals and Drugs Category
Enzymes and Coenzymes
Enzymes
Transferases
Phosphotransferases
Phosphotransferases (Alcohol Group Acceptor)
Protein Kinases
Protein Serine-Threonine Kinases
Positive Transcriptional Elongation Factor B

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Intracellular Signaling Peptides and Proteins
Protein Serine-Threonine Kinases
Positive Transcriptional Elongation Factor B

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Transcription Factors
Transcriptional Elongation Factors
Positive Transcriptional Elongation Factor B
Cyclin-Dependent Kinase 9
Cyclin T