Phosphatidylinositol Diacylglycerol-Lyase
A phosphorus-oxygen lyase found primarily in BACTERIA. The enzyme catalyzes the cleavage of a phosphoester linkage in 1-phosphatidyl-1D-myo-inositol to form 1D-myo-inositol 1,2-cyclic phosphate and diacylglycerol. The enzyme was formerly classified as a phosphoric diester hydrolase (EC 3.1.4.10) and is often referred to as a TYPE C PHOSPHOLIPASES. However it is now known that a cyclic phosphate is the final product of this enzyme and that water does not enter into the reaction.
Year introduced: 2004
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Subheadings:
Tree Number(s): D08.811.277.352.640.700.700.500, D08.811.520.650.800
MeSH Unique ID: D043265
Registry Number: EC 4.6.1.13
Entry Terms:
- Diacylglycerol-Lyase, Phosphatidylinositol
- Phosphatidylinositol Diacylglycerol Lyase
- 1-Phosphatidylinositol Phosphodiesterase
- 1 Phosphatidylinositol Phosphodiesterase
- Phosphodiesterase, 1-Phosphatidylinositol
- Monophosphatidylinositol Phosphodiesterase
- Phosphodiesterase, Monophosphatidylinositol
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