Receptor, Serotonin, 5-HT1D
A serotonin receptor subtype that is localized to the CAUDATE NUCLEUS; PUTAMEN; the NUCLEUS ACCUMBENS; the HIPPOCAMPUS, and the RAPHE NUCLEI. It plays a role as a terminal autoreceptor that regulates the rate of SEROTONIN release from nerve endings. This serotonin receptor subtype is closely related to and has similar drug binding properties as the 5-HT1B RECEPTOR, but is expressed at low levels. It is particularly sensitive to the agonist SUMATRIPTAN and may be involved in mediating the drug's antimigrane effect.
Year introduced: 2004
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Subheadings:
Tree Number(s): D12.776.543.750.670.800.100.200, D12.776.543.750.695.800.100.200, D12.776.543.750.720.670.100.750, D12.776.543.750.720.850.100.200
MeSH Unique ID: D044346
Entry Terms:
- 5-HT1D Receptor
- 5 HT1D Receptor
- Receptor, 5-HT1D
- 5-Hydroxytryptamine1D Receptor
- 5 Hydroxytryptamine1D Receptor
- Receptor, 5-Hydroxytryptamine1D
- 5-HT(1D) Receptor
- Serotonin 1D Receptors
- Receptors, Serotonin 1D
- Serotonin 1D Receptor
- Receptor, Serotonin 1D
- 5-HT(1Dalpha) Receptor
- Serotonin 1D Alpha Receptor
- 5-HT1Dalpha Receptor
- Receptor, Serotonin 1Dalpha
- Serotonin 1Dalpha Receptors
- Serotonin 1Dalpha Receptor
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