Inteins

The internal fragments of precursor proteins (INternal proTEINS) that are autocatalytically removed by PROTEIN SPLICING. The flanking fragments (EXTEINS) are ligated forming mature proteins. The nucleic acid sequences coding for inteins are considered to be MOBILE GENETIC ELEMENTS. Inteins are composed of self-splicing domains and an endonuclease domain which plays a role in the spread of the intein's genomic sequence. Mini-inteins are composed of the self-splicing domains only.

Year introduced: 2005

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Tree Number(s): G02.111.570.060.440

MeSH Unique ID: D047668

Entry Terms:

• Intein
• Introns, Protein
• Intron, Protein
• Protein Intron
• Protein Introns
• Intervening Protein Sequence
• Intervening Protein Sequences
• Protein Sequence, Intervening
• Protein Sequences, Intervening
• Sequence, Intervening Protein
• Sequences, Intervening Protein

Previous Indexing:

• Protein Splicing (1997-2004)

See Also:

• Protein Precursors
• Protein Splicing
• Exteins

All MeSH Categories
Phenomena and Processes Category
Chemical Phenomena
Biochemical Phenomena
Molecular Structure
Amino Acid Sequence
Inteins